Cognex Drug Review – Cognex Side Effects and Dosage

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Drug trade name- Cognex

Generic name- Tacrine

Group- Acetylcholinesterase Inhibitors


Introduction and Quick Information about Cognex:

Cognex (Tacrine) is one of the effective medications used for the treatment of mild to moderate dementia caused due to Alzheimer’s disease. This medication is also classified as an acetylcholinesterase inhibitor, which works by avoiding a specific enzyme (called acetylcholinesterase) from splitting down acetylcholine inside the brain. Acetylcholine is actually a sort of chemical which supports many brain functions, such as attention, memory, language, and reason.

Problems associated with insufficient acetylcholine within the brain may be accountable for some of the Alzheimer’s disease symptoms. Remember that individuals suffering from dementia generally have low levels of chemical, which is quite significant for the processes of thinking, memory, as well as reasoning.

Is Cognex Approved by FDA?

On 9th September, 1993, the U.S FDA (Food and Drug Administration) had given its approval to Cognex to treat dementia caused due to Alzheimer’s disease.

Usage and Benefits of Cognex:

Cognex (tacrine hydrochloride) is one of the prescribed medications licensed to treat mild to moderate Alzheimer’s disease. It is included in the class of drugs called acetylcholinesterase inhibitors.

Alzheimer’s disease is one of the kinds of dementia, which can affect a person’s memory, thought process, as well as his/her language. Well, there is not a specific cure for the Alzheimer’s disease, and the triggering factors which cause this condition, are not well understood. Initial signs of Alzheimer’s disease are generally confused with the usual changes associated with growing age. In due course, Alzheimer’s disease ruins a person’s ability to process information, think, and to function also.

Some of the common Alzheimer’s disease symptoms may include:

  • Worsening of language skills
  • Confusion
  • Poor judgment
  • Memory loss
  • Restlessness
  • Mood swings

The treatment for Alzheimer’s varies according to the different phases of Alzheimer’s. Medications to treat this condition are usually central considered very important. Cognex is approved to treat of mild to moderate Alzheimer’s disease. Don’t forget that it is neither a complete cure for Alzheimer’s, nor does it change the course of this disorder or prevent it from occurring. It can just assist you in improving memory, attention, language, reason, and the potential to carry out simple day-to-day tasks.

At times, your medical advisor may suggest you using Cognex to treat something other than Alzheimer’s disorder.

Some Off-label uses of Cognex may include the treatment of the following conditions-

  • Tourette syndrome
  • Attention deficit hyperactivity disorder (ADHD)

However, before following any of the aforementioned Cognex off-label use, just consult your doctor properly first.

Cognex Side Effects:

High liver enzymes, nausea, and diarrhea are some of the most common adverse effects associated with Cognex. Side effects which are rare but probable (take place in less than 1 % of individuals) include migraines, weight gain, as well as acne. While most of the Cognex side effects are negligible, some are extremely serious and thus, must be reported to a general practitioner at once, including

  • Hallucinations
  • Confusion
  • seizure (convulsions)
  • sudden or extreme changes in behavior
  • nausea
  • burning or pain while urinating
  • stomach pain
  • loss of appetite
  • low fever
  • dark urine
  • jaundice
  • clay-colored stools
  • diarrhea
  • mild nausea
  • vomiting
  • urinating more than usual
  • upset stomach
  • weight loss
  • agitation
  • depressed mood
  • skin rash
  • increased sweating
  • chills or fever
  • drowsiness
  • runny nose
  • cough
  • dizziness
  • lack of coordination
  • tired feeling
  • muscle or joint pain
  • weakness

Call your doctor immediately if you observe any of the aforementioned side effects.


General Recommended Dosages of Cognex:

If you really want your treatment with Cognex to give you positive benefits all the time, just take this medication in the exact quantity prescribed by your physician. Never try to take it in larger or smaller amounts, or for more than recommended periods.

You need to use this dug with one complete glass of water. Cognex can do wonders or benefit more if taken between the meals on an unfilled stomach. However, you can also take it along with your meals if this drug upsets your stomach.

It is quite essential to use Cognex on regular basis to get the most of the benefits.

Your general practitioner may occasionally change your Cognex dosing schedule to ensure if you are getting the best results from this drug.

When you initially start using Cognex, you might experience some minor side effects like vomiting, nausea, or diarrhea. These adverse effects may also take place when your dose is changed, or if you begin to take Tacrine again after long.

To see this medicine has not any harmful effects, your doctor may ask you to come for proper blood tests or checkups.  So pay regular visits to his clinic.

Store this medication at room temperature and away from heat and moisture.

In case I Miss my Dose?


People usually get frightened whenever they miss having their medication on the required time. However, there is no need to freak out, as you can take the Cognex missed dose whenever you remember at the same day. But if the time has appeared to take the next scheduled dose, then just skip the previously skipped one. Also, don’t take the extra Cognex dosage to compensate for the missed dosage.

In case I Take Overdose?


Overdose of Cognex may include severe vomiting or nausea, sweating, drooling, and feeling light-headed, slow heart rate, muscle weakness, fainting, coma, seizure (convulsions), or respiratory failure.

Call your doctor immediately if you believe you have taken this medication in excess or extra amounts.

Drug Interactions of Cognex:

If anticholinergic drugs, cholinergic medications, or nonsteroidal anti-inflammatory medicines are used along with Cognex, drug interactions can be occurred. These sorts of negative interactions may potentially minimize the efficacy of the medication or boost up the chances of having side effects. In order to cut down your chance of facing Cognex interactions, you should tell your medical advisor about all sorts of medicines you take. Some of the possible drugs which can interact with Cognex include:

  • Atropine (Atreza, Sal-Tropine, and others);
  • dicyclomine (Bentyl)
  • cimetidine (Tagamet)
  • fluvoxamine (Luvox)
  • donepezil (Aricept)
  • glycopyrrolate (Robinul)
  • galantamine (Razadyne)
  • mepenzolate (Cantil)
  • hyoscyamine (Levbid, Anaspaz, Nulev, Levsin, etc)
  • propantheline (Pro-Banthine)
  • methscopolamine (Pamine)
  • rivastigmine (Exelon)
  • scopolamine (Scopace, Maldemar, Transderm-Scop)
  • theophylline (Elixophyllin, Theo-Dur, Theolair, Uniphyl, Slo-Bid)

There can be some other drugs which may interact with tacrine. Thus, you should inform your doctor about all the over-the-counter and prescription medications you use, including minerals, vitamins, herbal products.

Life style and Food Habits you must Follow when on Cognex:

Do not use this drug in case you find yourselves allergic towards Cognex, or if you have ever had any liver problem or jaundice while using Cognex.

Before using tacrine, inform your physician if the following conditions run in you:

  • liver disease
  • a history of stomach ulcers
  • heart disease
  • urination problems or enlarged prostate
  • heart rhythm disorder like “sick sinus syndrome”
  • epilepsy or any other seizure disorder
  • asthma or chronic obstructive pulmonary disease (COPD)

Cognex can lead to side effects which may impair your reactions or thinking. So be attentive while you are driving.

How Safe is Cognex for Pregnant Women or Nursing mothers?

This medication can prove to be harmful to the health of an unborn baby if taken by pregnant women during pregnancy. Therefore, notify your general practitioner if you are expectant or plan to get pregnant during the treatment with Cognex. It is not yet known whether Cognex can pass in to the breast milk and harm a nursed baby or not. Thus, don’t use this drug without telling your physician if you breast-feed.

Complications and Conditions Possible due to Prolonged use of Cognex:

It is usually believed that the intake of a specific drug for a long period of time can make the users addicted. Well, it is not known whether Cognexcan do the same or not, but yes, it can make you resistant and also stop showing the same effects If you use it for years. Thus, it is recommendable not to quit using this medication without first consulting your healthcare professional. In case you stop using Tacrine suddenly, your condition may become worse.

Availability of the Cognex:

You can simply get Cognexfrom any government-approved drug shop after showing your prescription. You can come upon some online websites which are certified and also offer people the required drug together with some other useful discounts.

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